Look at this ugly little packed bubble chart. They are horrible little charts. Our eyes are not able to differentiate quantities in spherical formats. Okay maybe some do look bigger but by how much? I picked this monstrosity because while searching through clinicaltrials.gov for recruiting trials sorted geographically I noticed how a lack of standardization during data collection can leave chaos.
Another obvious data flaw is the wide variety of labels for studies within the database. What influences the classification scheme by colorectal cancer, colon cancer, colorectal carcinoma or even colorectal adenocarcinoma?
Can you see why this might be relevant in this current healthcare ecosystem where the prices of oncology drugs continue to escalate but the clinical efficacy is ill-defined?
Progression-free survival is a recurrent primary endpoint used to rate and compare randomized clinical trial findings but what does this mean for point of care decisions between community oncologists and their patients with colorectal cancer?