Listen to the scope and promise of this important initiative. Patrick Soon-Shiong is a powerful physician (the richest doctor in the world) and multibillionaire surgeon and entrepreneur. The influence of a consortium of this magnitude will be closely observed. March 1 is the launch and only time will tell.
At the very least, we can use quantitative evidence to target chemotherapy quantifiably to determine if resistance exists--like antibiotics.
Moonshot 2020 in the news...
“The president mentioned the moonshot in his State of the Union speech, which has put us on the stage and in the news,” said Soon-Shiong. “The opportunity to change healthcare forever, in the face of immunotherapy use, is upon us. It’s taken us 15 years to get here.” Explaining that our body has the innate capacity to immunize itself against infections as well as abnormal growth, he added, “I have personally struggled with the fact that we destroy our immune system with chemotherapy, and then boost the immune system with checkpoint inhibitors.” - Patrick Soon-Shiung
Our immune system contains dendritic cells, NK cells, and T-cells. Basically we are destroying immune systems with chemotherapy and following up with checkpoint inhibitors of T-cells that we just obliterated--doesn't make sense. Dr. Soon-Shiung actually shared that the current approach of maximum tolerated chemotherapy causes micro-metasis--revealing counterintuitive findings from research.
“The president mentioned the moonshot in his State of the Union speech, which has put us on the stage and in the news. The opportunity to change healthcare forever, in the face of immunotherapy use, is upon us. It’s taken us 15 years to get here. I have personally struggled with the fact that we destroy our immune system with chemotherapy, and then boost the immune system with checkpoint inhibitors.” --Patrick Soon-Shiong
Dr. Patrick Soon-Shiong states the platform can help reduce toxicities and avoid unnecessary treatment with chemotherapy agents.
“We can measure the resistance factor before treating patients with the drug…similar to how we measure antibiotic resistance in patients before starting them on an antibiotic.”
You can navigate to JP Morgan Healthcare Conference webcasts and click on the National Immunotherapy Coalition: Cancer Moonshot 2020 keynote special presentations.
If you listen to the recording, Dr Soon-Shiong recommends a book, The Death of Cancer
Please like, share, and join the dialogue...more details will evolve at Cancer The Brand over the coming months.
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In a world of "evidence-based" medicine I am a bigger fan of practice-based evidence.
Remember the quote by Upton Sinclair...
“It is difficult to get a man to understand something, when his salary depends upon his not understanding it!”